© 2020 - MeltPrep I All rights reserved. I General Terms & Conditions I Impressum I

Frequently Asked Questions (FAQ)

Let's get straight to it.

Do you have questions ? We have answers. Browse the topics below to find what you're looking for.

#1: How much material do I need to make a sample?

Just the right amount.

If you work with formulations comprising different substances it must be homogeneous and micronized, preferable in the small micrometer particle size range.

With 2 mm diameter samples and 1 mm in height, that sample would require only a few mg of material.

 

#2: Who uses VCM Technology?

Pioneers.

In pharma it is used for Hot Melt Extrusion developments from 4 of the top 10 companies. We work with Merck on a Publication where we used our VCM technology for screening studies of PVA (Poly-Vinyl-Alcohol), to showcase the advantages of this substance in direct comparison to other carrier materials.

Pharma

Food

Plastics

We do have some testimonials from different industries, click           to visit the related page.

 

#3: What is the minimum thickness of the sample?

Wide range of choices.

We suggest thicknesses between 0.1 and 10 mm for the VCM samples. Thickness may also depend on the material characteristics.

If you have elastic polymers like TPU (Thermoplastic Poly Urethane) or EVA (Ethyl-Vinyl-Acetate) you can also reach thinner layers in the range of 50 µm for example. 

 

#4: How many layers can you make?

Multiple combinations.

We have demonstrated in the NuvaRing Screening (click          to see the publication) a system of 3 layers. We do have some customers working on implants which are evaluating system with up to 10 different layers. Here its important to note that the materials need to be compatible. Adhesion, similar melting points and similar viscosity levels at the processing temperatures.

VCM process

VCM process

Homogeneous sample

Homogeneous sample

To obtain a multilayer sample, place both samples again in the VCM and repeat the VCM process with the same conditions.

Homogeneous multilayered sample

 

#5: Can the PTFE foils be reused?

Comfortable and easy.

Yes, the foils are reusable. The PTFE Foils are glass-fiber reinforced. That mean the Teflon does not flow and keeps its shape. So that they can be reused several times. As a rule of thumb, we recommend using them 10 times before they should be replaced. 

 

#5: Can I use the VCM technology at constant temperature continuously for several hours?

Made to last.

Yes, there is no inconvenience in using the VCM technology during a long period of time at constant temperature (i.e. 60 °C). The materials are prepared for a long exposure. You can work with VCM tool up to 200 °C for several hours, while up to 300 °C we recommend to use it for short-time operations.

 

Do you have more questions?

Ask for support. Our experts are always happy to help you.