VCM_HME ASD and implant formulation screening

VCM Publications

MeltPrep accelerates research.

Good sample quality is vital for reliable and reproducible material characterizations. Scientific users and quality managers get the most out of their characterization from flawless samples. VCM is a novel approach to screening polymers using a minimum quantity of active pharmaceutical ingredients. Read our latest publication to find out.

Pharmaceutical Applications

VCM Technology is designed for highly challenging pharmaceutical requirements. Our system's benefits have already attracted the attention of different industries. Read the peer-reviewed publications and explore the different pharmaceutical applications involving VCM Technology.

Title	Authors	Company/Institution	Year
Prediction of Solvent Penetration Rate-Limited Release of Drug from Amorphous Solid Dispersion Discs of Various Geometries	Shuaiqian Men	University of Maryland	2026
In vitro release testing of levonorgestrel intrauterine systems: Correlation of accelerated release rates in organic/aqueous release media to Hansen Solubility Parameters	Rokon Uz Zaman	U.S. Food and Drug Administration, University of Texas at Austin	2026
Unlocking the potential of alkaline polymethacrylates via ionic crosslinking in amorphous solid dispersions	Lukas Mild	University of Bonn	2026
Predicting Drug Loading Capacity for PLA-Amorphous Drug System Using Hansen Solubility Parameters	Artūrs Paulausks	Rīga Stradiņš University, Lithuanian University of Health Sciences, Baltic Biomaterials Centre of Excellence	2026
Manufacturing and testing of a polymer formulation for long-time release delivery of antisense oligonucleotides in hiPSC-derived motoneurons	Maria Victoria Martinez-Dominguez	German Center for Neurodegenerative Diseases (DZNE), Ulm University, Neurozentrum Ulm (NCU), University of Bonn	2026
Role of Dissolution Medium pH in the Release Behavior of Basic Drug–Copovidone Amorphous Solid Dispersions	Taiga Uekusa	Purdue University, Eli Lilly and Company	2026
Long-acting delivery of a model monoclonal antibody from ethylene vinyl acetate implants at a high loading: Drug release and protein stability Copy	Yu Tong Tam	Genentech Inc., Celanese Corp.	2026
Design of experiment optimization of hydrocortisone ocular minitablets via vacuum compression molding with scalability assessment by fused deposition modeling	Alaa Y. Darwesh	University of Mississippi, Mansoura University, University of Texas at Austin	2025
Characterization of Different Copovidone Grades as Carrier Materials in Hot Melt Extrusion of Amorphous Solid Dispersions	Marvin Daalmann	TU Dortmund University, INVITE GmbH, Ashland Life Sciences R&D	2025
Vacuum compression-molded polyvinyl alcohol microneedles for sustained three-day transdermal delivery of palonosetron hydrochloride	Meheli Ghosh	Mercer University, MilliporeSigma a Business of Merck KGaA	2025
Drug Delivery – Recent Trends, Enabling Technologies, In-Vitro-In-Vivo Predictions & Personalized Medicine	Jens Morgenthaler	Losan Pharma GmbH	2025
3D-printed Gabapentin-loaded Implants for Sustained Release: Leveraging 3D Printing and Hot Melt Extrusion (HME) for Customizable Drug Delivery	Baher A. Daihom	The University of Texas at Austin, Cairo University, American University in Iraq-Baghdad, Assiut University, The University of Mississippi	2025

Material Characterization

Our customers use flawless VCM samples for various measurement methods such as DSC, hardness, notch impact strength, heat capacity, solubility, DMTA, microscopy, etc. Discover how researchers used VCM Technology for their material characterization research projects.

Title	Authors	Company/Institution	Year
Understanding Enhanced Melt Memory in Poly(Octamethylene Carbonate)-Based Random Copolycarbonates with Mixed Isodimorphic/Isomorphic Crystallization	Yilong Liao	Tianjin University, POLYMAT, University of the Basque Country UPV/EHU, Centro de Física de Materiales (CFM-MPC),	2026
Effects of the Environment in Hydrogen-Bonded Polymers	Chenming Li	Martin-Luther-Universität Halle- Wittenberg	2025
Biobased Chemical Recycling: Aminolysis of PET using Renewable Reagents and Monomers to Synthesize New Semi-aromatic Polyamides	Sathiska Kaumadi	Clemson University, Pacific Northwest National Laboratory, University of Delaware	2025
Probing the Influence of Water on the Molecular Mobility of PVP/VA using Terahertz Spectroscopy	Supawan Santitewagun	University of Cambridge	2025
Engineering the Interface of Interfacially-Locked Graphene in Electrically Conductive Poly(ethylene furanoate)/Polyethylene (PEF/PE) Blends	Safa Ahmed	United Arab Emirates University (UAEU), KU Leuven, Eindhoven University of Technology, University of Niagara Falls	2025
Chemical modification of poly(isosorbide carbonate)-based copolymers with boronic acids and the ammonolysis of the modified copolymers	Kazuaki Rikiyama	Chiba University	2025
Effect of Noncrystallizable Comonomers in Polyethylene on Crystallization, Semicrystalline Morphology, Intracrystalline Dynamics, and Linear Mechanical Properties	Shiyan Li	Changchun Institute of Applied Chemistry, Martin-Luther-Universität Halle-Wittenberg	2025
Toughening Brittle Poly(ethylene Furanoate) with Linear Low-Density Polyethylene via Interface Modulation Using Reactive Compatibilizers	Safa Ahmed	United Arab Emirates University, KU Leuven, University of Niagara Falls	2025
Frontal polymerization of thiol–acrylate covalent adaptable networks	Christoph Schmidleitner	Polymer Competence Center Leoben GmbH	2025
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024
How entanglements determine the morphology of semicrystalline polymers	Zefan Wang	Martin Luther University	2023
Molecular-Level Control of Thermal and Morphological Transitions in Semi-Aromatic Polyamides by Cu(I)-Catalyzed Azide–Alkyne Click Polymerization	Ozcan Altintas	ExxonMobil Technology and Engineering Company	2023

VChamber in Action: Scientific Insights

Explore how the VChamber transforms research with its precise vacuum drying capabilities and adaptability across diverse applications. Discover the latest publications highlighting its impact on innovation and learn how it contributes to groundbreaking advancements in science and technology.

Title	Authors	Company/Institution	Year
Insights into the Capacity Fade of High-Voltage Lithium Cathodes in Solid Polymer Electrolyte Cells	Idan Bar-lev	The Hebrew University of Jerusalem	2025
Enhancing Efficiency, Stability, and Cycle Life of Lithium Metal Electrodeposition in Dry Solid-State Polymer Electrolytes	Idan Bar-lev	The Hebrew University of Jerusalem, Boston University, Ariel University	2024
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024

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