ExtruVis Publications

Provide insights.

Residence Time Distributions give you insights into the flow behavior of your process, which is of the utmost importance for process development during scale-up and during troubleshooting when something goes wrong. Explore the peer-reviewed publications written by our users and what they have derived from their measurements.

Title	Authors	Company/Institution	Year
Material Transport Characteristics in Planetary Roller Melt Granulation	Tom Lang	TU Dortmund University	2023
Continuous wet granulation and fluid-bed drying – An experimental investigation of a new revolutionary system	Robin Meier	L.B. Bohle Maschinen und Verfahren GmbH	2023
Visualization of the granule temperature using thermal imaging to improve understanding of the granulation mechanism in continuous twin-screw melt granulation	S. Van de Steene	Ghent University	2023
Integrated Continuous Wet Granulation and Drying: Process Evaluation and Comparison with Batch Processing	Seth P. Forster	Merck & Co., Inc., Organon & Co., Inc., L.B. Bohle Maschinen und Verfahren GmbH	2023
Applications of machine vision in pharmaceutical technology: A review	Dorián László Galata	Budapest University of Technology and Economics, Semmelweis University	2021
Optimization of residence time distribution in RCDG and an assessment of its applicability in continuous manufacturing	Annika Wilms	Heinrich Heine University Düsseldorf, INVITE GmbH	2021
Melt granulation: A comparison of granules produced via high-shear mixing and twin-screw granulation	Kristina E. Steffens	University of Bonn	2020
Processing of Polyvinyl Acetate Phthalate in Hot-Melt Extrusion—Preparation of Amorphous Solid Dispersions	Marius Monschke	University of Bonn	2020
Twin screw granulation: A simpler re-derivation of quantifying fill level	Aquino L. Mundozah	University of Sheffield	2020
Important elements in continuous granule drying processes	Robin Meier	L.B. Bohle Maschinen und Verfahren GmbH	2020
Assessment of volumetric scale-up law for processing of a sustained release formulation on co-rotating hot-melt extruders	Jeroen Van Renterghem	Thermo Fisher Scientific, Laboratory of Pharmaceutical Process Analytical Technology Ghent	2019
Continuous manufacturing of a pharmaceutical cream: Investigating continuous powder dispersing and residence time distribution (RTD)	N. Bostijn	Ghent University, Johnson & Johnson Global Technical Operations	2019
Hydrophobic/hydrophilic powders: Practical implications of screw element type on the reduction of fines in twin screw granulation	Aquino L. Mundozah	University of Sheffield, GSK	2019
Development and Performance of a Highly Sensitive Model Formulation Based on Torasemide to Enhance Hot-Melt Extrusion Process Understanding and Process Development	Rachel C. Evans	AbbVie Deutschland GmbH & Co. KG, University of Bonn	2018
Numerical simulation of hot-melt extrusion processes for amorphous solid dispersions using model-based melt viscosity	Esther S. Bochmann	University of Bonn, BASF SE	2018
Impact of fill-level in twin-screw granulation on critical quality attributes of granules and tablets	Robin Meier	Heinrich Heine University, Novartis AG	2017
Experimental determination of residence time distribution in continuous dry granulation	Haress Mangal	Heinrich Heine University	2017
Granule size distributions after twin-screw granulation – Do not forget the feeding systems	Robin Meier	Heinrich Heine University, Technical University Dortmund, Novartis AG	2016

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