VCM_HME ASD and implant formulation screening

VCM Publications

MeltPrep accelerates research.

Good sample quality is vital for reliable and reproducible material characterizations. Scientific users and quality managers get the most out of their characterization from flawless samples. VCM is a novel approach to screening polymers using a minimum quantity of active pharmaceutical ingredients. Read our latest publication to find out.

Pharmaceutical Applications

VCM Technology is designed for highly challenging pharmaceutical requirements. Our system's benefits have already attracted the attention of different industries. Read the peer-reviewed publications and explore the different pharmaceutical applications involving VCM Technology.

Title	Authors	Company/Institution	Year
Design of experiment optimization of hydrocortisone ocular minitablets via vacuum compression molding with scalability assessment by fused deposition modeling	Alaa Y. Darwesh	University of Mississippi, Mansoura University, University of Texas at Austin	2025
Research progress of vacuum compression molding technology in pharmaceutical fields	Yixuan Wang	China Pharmaceutical University, Zhejiang Yongning Pharmaceutical Co.	2025
Characterization of Different Copovidone Grades as Carrier Materials in Hot Melt Extrusion of Amorphous Solid Dispersions	Marvin Daalmann	TU Dortmund University, INVITE GmbH, Ashland Life Sciences R&D	2025
Vacuum compression-molded polyvinyl alcohol microneedles for sustained three-day transdermal delivery of palonosetron hydrochloride	Meheli Ghosh	Mercer University, MilliporeSigma a Business of Merck KGaA	2025
Drug Delivery – Recent Trends, Enabling Technologies, In-Vitro-In-Vivo Predictions & Personalized Medicine	Jens Morgenthaler	Losan Pharma GmbH	2025
3D-printed Gabapentin-loaded Implants for Sustained Release: Leveraging 3D Printing and Hot Melt Extrusion (HME) for Customizable Drug Delivery	Baher A. Daihom	The University of Texas at Austin, Cairo University, American University in Iraq-Baghdad, Assiut University, The University of Mississippi	2025
Long-acting drug delivery systems: Current landscape and future prospects	Eneko Larrañeta	Queen’s University Belfast, Universidad de Sevilla	2025
Dual-extruder 3D-printing of biodegradable subcutaneous implants for controlled drug delivery	Bianca Brandl	Research Center Pharmaceutical Engineering GmbH, University of Graz, InnoCore Pharmaceuticals, FH Upper Austria Research & Development GmbH, Hage3D GmbH, Graz University of Technology	2025
The More the Better?─Vitamin E TPGS as a Release Enhancer for Ritonavir/PVPVA Amorphous Solid Dispersions	Ineke Fahrig	TU Dortmund University, AbbVie Deutschland GmbH & Co. KG	2025
Preparation, characterisation, and testing of reservoir-based implantable devices loaded with tizanidine and lidocaine	Camila J. Picco	Queen’s University Belfast, Ulster University, University of Seville	2025
Water-Assisted Drying of PVPVA-Based Amorphous Solid Dispersions	Jana Kerkhoff	TU Dortmund University	2025
Expediting 3D printed medication development using vacuum compression moulding	Anna Kirstine Jørgensen	University College London, Universidade de Santiago de Compostela, FABRX Ltd., FABRX Artificial Intelligence	2025

Material Characterization

Our customers use flawless VCM samples for various measurement methods such as DSC, hardness, notch impact strength, heat capacity, solubility, DMTA, microscopy, etc. Discover how researchers used VCM Technology for their material characterization research projects.

Title	Authors	Company/Institution	Year
Understanding Enhanced Melt Memory in Poly(Octamethylene Carbonate)-Based Random Copolycarbonates with Mixed Isodimorphic/Isomorphic Crystallization	Yilong Liao	Tianjin University, POLYMAT, University of the Basque Country UPV/EHU, Centro de Física de Materiales (CFM-MPC),	2026
Effects of the Environment in Hydrogen-Bonded Polymers	Chenming Li	Martin-Luther-Universität Halle- Wittenberg	2025
Biobased Chemical Recycling: Aminolysis of PET using Renewable Reagents and Monomers to Synthesize New Semi-aromatic Polyamides	Sathiska Kaumadi	Clemson University, Pacific Northwest National Laboratory, University of Delaware	2025
Probing the Influence of Water on the Molecular Mobility of PVP/VA using Terahertz Spectroscopy	Supawan Santitewagun	University of Cambridge	2025
Engineering the Interface of Interfacially-Locked Graphene in Electrically Conductive Poly(ethylene furanoate)/Polyethylene (PEF/PE) Blends	Safa Ahmed	United Arab Emirates University (UAEU), KU Leuven, Eindhoven University of Technology, University of Niagara Falls	2025
Chemical modification of poly(isosorbide carbonate)-based copolymers with boronic acids and the ammonolysis of the modified copolymers	Kazuaki Rikiyama	Chiba University	2025
Effect of Noncrystallizable Comonomers in Polyethylene on Crystallization, Semicrystalline Morphology, Intracrystalline Dynamics, and Linear Mechanical Properties	Shiyan Li	Changchun Institute of Applied Chemistry, Martin-Luther-Universität Halle-Wittenberg	2025
Toughening Brittle Poly(ethylene Furanoate) with Linear Low-Density Polyethylene via Interface Modulation Using Reactive Compatibilizers	Safa Ahmed	United Arab Emirates University, KU Leuven, University of Niagara Falls	2025
Frontal polymerization of thiol–acrylate covalent adaptable networks	Christoph Schmidleitner	Polymer Competence Center Leoben GmbH	2025
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024
How entanglements determine the morphology of semicrystalline polymers	Zefan Wang	Martin Luther University	2023
Molecular-Level Control of Thermal and Morphological Transitions in Semi-Aromatic Polyamides by Cu(I)-Catalyzed Azide–Alkyne Click Polymerization	Ozcan Altintas	ExxonMobil Technology and Engineering Company	2023

VChamber in Action: Scientific Insights

Explore how the VChamber transforms research with its precise vacuum drying capabilities and adaptability across diverse applications. Discover the latest publications highlighting its impact on innovation and learn how it contributes to groundbreaking advancements in science and technology.

Title	Authors	Company/Institution	Year
Insights into the Capacity Fade of High-Voltage Lithium Cathodes in Solid Polymer Electrolyte Cells	Idan Bar-lev	The Hebrew University of Jerusalem	2025
Enhancing Efficiency, Stability, and Cycle Life of Lithium Metal Electrodeposition in Dry Solid-State Polymer Electrolytes	Idan Bar-lev	The Hebrew University of Jerusalem, Boston University, Ariel University	2024
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024

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