VCM_HME ASD and implant formulation screening

VCM Publications

MeltPrep accelerates research.

Good sample quality is vital for reliable and reproducible material characterizations. Scientific users and quality managers get the most out of their characterization from flawless samples. VCM is a novel approach to screening polymers using a minimum quantity of active pharmaceutical ingredients. Read our latest publication to find out.

Pharmaceutical Applications

VCM Technology is designed for highly challenging pharmaceutical requirements. Our system's benefits have already attracted the attention of different industries. Read the peer-reviewed publications and explore the different pharmaceutical applications involving VCM Technology.

Title	Authors	Company/Institution	Year
Addressing Solubility and Analytical Challenges in Transdermal Nystatin Microneedle Formulation	Sydney Laughlin	East Tennessee State University	2025
Development of vacuum compression molded tablets with rapid drug release and a comparison of dissolution profiles between molded and FDM 3D-printed tablets	Nirali G. Patel	St. John’s University	2025
FDM 3D-printed oral dosage form of prednisolone – Improvement of printability and influencing drug release	Zoltán Márk Horváth	Rīga Stradiņš University, University of Latvia, Queen’s University Belfast	2025
Fabrication and characterization of dissolving microneedles combining digital light processing and vacuum compression molding technique for the transdermal delivery of rivastigmine	Paraskevi Kyriaki Monou	Aristotle University of Thessaloniki, Delta Pharmaceutics Ltd, International Hellenic University, University of Patras, University of Southampton	2025
Towards Enhanced Solubility of Cannabidiol: Preparation and Evaluation of Cannabidiol Solid Dispersions Using Vacuum Compression Molding	Achref Cherif	University of Mississippi	2025
Formulation Development for 3D Printing of Immediate Release Cabozantinib Tablets with Personalized Dosage	Jonas Lenhart	Eberhard Karls University	2025
Predicting the Release Mechanism of Amorphous Solid Dispersions: A Combination of Thermodynamic Modeling and In Silico Molecular Simulation	Stefanie Walter	AbbVie Deutschland	2024
Dosage by design – 3D printing individualized cabozantinib tablets with immediate release	Jonas Lenhart	Eberhard Karls University	2024
An alternative filament fabrication method as the basis for 3D-printing personalized implants from elasticethylene vinyl acetate copolymer	Bianca Brandl	Research Center Pharmaceutical Engineering GmbH, Celanese, MeltPrep, FH Upper Austria Research &Development GmbH	2024
Dispersion state analysis in hot melt extruded, highly drug-loaded 3D printing filaments applying Raman microscopy	Marius Tidau	TU Braunschweig	2024
Measuring and Modeling of Melt Viscosity for Drug Polymer Mixtures	Markus Thommes	TU Dortmund	2024
Optimizing extrusion processes and understanding conformational changes in itraconazole amorphous solid dispersions using in-line UV–Vis spectroscopy and QbD principles	Hetvi Triboandas	De Montfort University, GlaxoSmithKline, Applied Materials	2024

Material Characterization

Our customers use flawless VCM samples for various measurement methods such as DSC, hardness, notch impact strength, heat capacity, solubility, DMTA, microscopy, etc. Discover how researchers used VCM Technology for their material characterization research projects.

Title	Authors	Company/Institution	Year
Understanding Enhanced Melt Memory in Poly(Octamethylene Carbonate)-Based Random Copolycarbonates with Mixed Isodimorphic/Isomorphic Crystallization	Yilong Liao	Tianjin University, POLYMAT, University of the Basque Country UPV/EHU, Centro de Física de Materiales (CFM-MPC),	2026
Effects of the Environment in Hydrogen-Bonded Polymers	Chenming Li	Martin-Luther-Universität Halle- Wittenberg	2025
Biobased Chemical Recycling: Aminolysis of PET using Renewable Reagents and Monomers to Synthesize New Semi-aromatic Polyamides	Sathiska Kaumadi	Clemson University, Pacific Northwest National Laboratory, University of Delaware	2025
Probing the Influence of Water on the Molecular Mobility of PVP/VA using Terahertz Spectroscopy	Supawan Santitewagun	University of Cambridge	2025
Engineering the Interface of Interfacially-Locked Graphene in Electrically Conductive Poly(ethylene furanoate)/Polyethylene (PEF/PE) Blends	Safa Ahmed	United Arab Emirates University (UAEU), KU Leuven, Eindhoven University of Technology, University of Niagara Falls	2025
Chemical modification of poly(isosorbide carbonate)-based copolymers with boronic acids and the ammonolysis of the modified copolymers	Kazuaki Rikiyama	Chiba University	2025
Effect of Noncrystallizable Comonomers in Polyethylene on Crystallization, Semicrystalline Morphology, Intracrystalline Dynamics, and Linear Mechanical Properties	Shiyan Li	Changchun Institute of Applied Chemistry, Martin-Luther-Universität Halle-Wittenberg	2025
Toughening Brittle Poly(ethylene Furanoate) with Linear Low-Density Polyethylene via Interface Modulation Using Reactive Compatibilizers	Safa Ahmed	United Arab Emirates University, KU Leuven, University of Niagara Falls	2025
Frontal polymerization of thiol–acrylate covalent adaptable networks	Christoph Schmidleitner	Polymer Competence Center Leoben GmbH	2025
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024
How entanglements determine the morphology of semicrystalline polymers	Zefan Wang	Martin Luther University	2023
Molecular-Level Control of Thermal and Morphological Transitions in Semi-Aromatic Polyamides by Cu(I)-Catalyzed Azide–Alkyne Click Polymerization	Ozcan Altintas	ExxonMobil Technology and Engineering Company	2023

VChamber in Action: Scientific Insights

Explore how the VChamber transforms research with its precise vacuum drying capabilities and adaptability across diverse applications. Discover the latest publications highlighting its impact on innovation and learn how it contributes to groundbreaking advancements in science and technology.

Title	Authors	Company/Institution	Year
Insights into the Capacity Fade of High-Voltage Lithium Cathodes in Solid Polymer Electrolyte Cells	Idan Bar-lev	The Hebrew University of Jerusalem	2025
Enhancing Efficiency, Stability, and Cycle Life of Lithium Metal Electrodeposition in Dry Solid-State Polymer Electrolytes	Idan Bar-lev	The Hebrew University of Jerusalem, Boston University, Ariel University	2024
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024

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