VCM_HME ASD and implant formulation screening

VCM Publications

MeltPrep accelerates research.

Good sample quality is vital for reliable and reproducible material characterizations. Scientific users and quality managers get the most out of their characterization from flawless samples. VCM is a novel approach to screening polymers using a minimum quantity of active pharmaceutical ingredients. Read our latest publication to find out.

Pharmaceutical Applications

VCM Technology is designed for highly challenging pharmaceutical requirements. Our system's benefits have already attracted the attention of different industries. Read the peer-reviewed publications and explore the different pharmaceutical applications involving VCM Technology.

Title	Authors	Company/Institution	Year
Addressing Solubility and Analytical Challenges in Transdermal Nystatin Microneedle Formulation	Sydney Laughlin	East Tennessee State University	2025
Development of vacuum compression molded tablets with rapid drug release and a comparison of dissolution profiles between molded and FDM 3D-printed tablets	Nirali G. Patel	St. John’s University	2025
FDM 3D-printed oral dosage form of prednisolone – Improvement of printability and influencing drug release	Zoltán Márk Horváth	Rīga Stradiņš University, University of Latvia, Queen’s University Belfast	2025
Fabrication and characterization of dissolving microneedles combining digital light processing and vacuum compression molding technique for the transdermal delivery of rivastigmine	Paraskevi Kyriaki Monou	Aristotle University of Thessaloniki, Delta Pharmaceutics Ltd, International Hellenic University, University of Patras, University of Southampton	2025
Towards Enhanced Solubility of Cannabidiol: Preparation and Evaluation of Cannabidiol Solid Dispersions Using Vacuum Compression Molding	Achref Cherif	University of Mississippi	2025
Formulation Development for 3D Printing of Immediate Release Cabozantinib Tablets with Personalized Dosage	Jonas Lenhart	Eberhard Karls University	2025
Predicting the Release Mechanism of Amorphous Solid Dispersions: A Combination of Thermodynamic Modeling and In Silico Molecular Simulation	Stefanie Walter	AbbVie Deutschland	2024
Dosage by design – 3D printing individualized cabozantinib tablets with immediate release	Jonas Lenhart	Eberhard Karls University	2024
An alternative filament fabrication method as the basis for 3D-printing personalized implants from elasticethylene vinyl acetate copolymer	Bianca Brandl	Research Center Pharmaceutical Engineering GmbH, Celanese, MeltPrep, FH Upper Austria Research &Development GmbH	2024
Dispersion state analysis in hot melt extruded, highly drug-loaded 3D printing filaments applying Raman microscopy	Marius Tidau	TU Braunschweig	2024
Measuring and Modeling of Melt Viscosity for Drug Polymer Mixtures	Markus Thommes	TU Dortmund	2024
Optimizing extrusion processes and understanding conformational changes in itraconazole amorphous solid dispersions using in-line UV–Vis spectroscopy and QbD principles	Hetvi Triboandas	De Montfort University, GlaxoSmithKline, Applied Materials	2024

Material Characterization

Our customers use flawless VCM samples for various measurement methods such as DSC, hardness, notch impact strength, heat capacity, solubility, DMTA, microscopy, etc. Discover how researchers used VCM Technology for their material characterization research projects.

Title	Authors	Company/Institution	Year
Characterization of the temperature and frequency dependency of the complex Poisson’s ratio using a novel combined torsional-axial rheometer	José Alberto Rodríguez Agudo	Anton Paar	2023
Lignin-based benzoxazines: A tunable key-precursor for the design of hydrophobic coatings, fire resistant materials and catalyst-free vitrimers	Antoine Adjaoud	Luxembourg Institute of Science and Technology, University of Luxembourg	2023
The Semicrystalline Morphology of Polybutylene Succinate Supports a General Scheme Based on Intracrystalline Dynamics	Qiang Yu	Martin Luther University	2023
Synthesis and Characterization of Quadrupolar-Hydrogen-Bonded Polymeric Ionic Liquids for Potential Self-Healing Electrolytes	Chenming Li	Martin Luther University	2022
Open-Celled Foams of Polyethersulfone/Poly(N-vinylpyrrolidone) Blends for Ultrafiltration Applications	Aniket Raje	Institute of Membrane Research	2022
Design of Polymeric Zwitterionic Solid Electrolytes with Superionic Lithium Transport	Seamus D. Jones	University of California	2022
Influence of Carbon Dioxide on the Glass Transition of Styrenic and Vinyl Pyridine Polymers: Comparison of Calorimetric, Creep, and Rheological Experiments	Felix Harden	Helmholtz-Zentrum Hereon	2022
How Shape Memory Effects can Contribute to Improved Self-Healing Properties in Polymer Materials	Elizaveta V. Selezneva	A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences	2021
Terahertz Spectroscopy: An Investigation of the Structural Dynamics of Freeze-Dried Poly Lactic-co-glycolic Acid Microspheres	Talia A. Shmool	University of Cambridge, AstraZeneca	2019
Rheology in shear and elongation and dielectric spectroscopy of polystyrene-block-poly(4-vinylpyridine) diblock copolymers	Tarek Kollmetz	Helmholtz-Zentrum Geesthacht	2017

VChamber in Action: Scientific Insights

Explore how the VChamber transforms research with its precise vacuum drying capabilities and adaptability across diverse applications. Discover the latest publications highlighting its impact on innovation and learn how it contributes to groundbreaking advancements in science and technology.

Title	Authors	Company/Institution	Year
Insights into the Capacity Fade of High-Voltage Lithium Cathodes in Solid Polymer Electrolyte Cells	Idan Bar-lev	The Hebrew University of Jerusalem	2025
Enhancing Efficiency, Stability, and Cycle Life of Lithium Metal Electrodeposition in Dry Solid-State Polymer Electrolytes	Idan Bar-lev	The Hebrew University of Jerusalem, Boston University, Ariel University	2024
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024

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