VCM_HME ASD and implant formulation screening

VCM Publications

MeltPrep accelerates research.

Good sample quality is vital for reliable and reproducible material characterizations. Scientific users and quality managers get the most out of their characterization from flawless samples. VCM is a novel approach to screening polymers using a minimum quantity of active pharmaceutical ingredients. Read our latest publication to find out.

Pharmaceutical Applications

VCM Technology is designed for highly challenging pharmaceutical requirements. Our system's benefits have already attracted the attention of different industries. Read the peer-reviewed publications and explore the different pharmaceutical applications involving VCM Technology.

Title	Authors	Company/Institution	Year
Exploring Orodispersible Films Containing the Proteolysis Targeting Chimera ARV-110 in Hot Melt Extrusion and Solvent Casting Using Polyvinyl Alcohol	Valentina Meloni	Merck Life Science KGaA, Merck Chemicals (Shanghai)	2024
Counteracting the Loss of Release for Indomethacin-Copovidone ASDs	Dominik Borrmann	TU Dortmund	2024
In Situ Imaging of Subcutaneous Drug Delivery Systems Using Microspatially Offset Low-Frequency Raman Spectroscopy	Ka̅rlis Be̅rziņš	University of Copenhagen	2024
Evaluation of Printability of PVA-Based Tablets from Powder and Assessment of Critical Rheological Parameters	Jonas Lenhart	Eberhard Karls University	2024
Co-sorption of volatile components in polymer-based pharmaceutical formulations	Jana Kerkhoff	TU Dortmund, INVITE GmbH	2024
From microchips to microneedles: semiconductor shear testers as a universal solution for transverse load analysis of microneedle mechanical performance	Kazim Haider	University of Calgary, University College Dublin	2024
Concordance of vacuum compression molding with spray drying in screening of amorphous solid dispersions of itraconazole	James Polli	University of Maryland	2024
Use of Poly(vinyl alcohol) in Spray-Dried Dispersions: Enhancing Solubility and Stability of Proteolysis Targeting Chimeras	Lena Mareczek	Merck Life Science KGaA, Technical University of Darmstadt	2024
Exploring Vacuum Compression Molding as a Preparation Method for Flexible-Dose Pediatric Orodispersible Film	Dana Hales	Iuliu Hatieganu University of Medicine and Pharmacy	2024
Toward high-resolution 3D-printing of pharmaceutical implants – A holistic analysis of relevant material properties and process parameters	Martin Spoerk	Research Center Pharmaceutical Engineering GmbH	2024
Beyond Skin-Deep: Fabrication of Nystatin-Loaded Microneedles For Enhanced and Sustained Effects against Candida albicans	Zachary Kennedy	East Tennessee State University	2024
Microscope-enabled disc dissolution system: Concordance between drug and polymer dissolution from an amorphous solid dispersion disc and visual disc degradation	Shuaiqian Men	University of Maryland	2024

Material Characterization

Our customers use flawless VCM samples for various measurement methods such as DSC, hardness, notch impact strength, heat capacity, solubility, DMTA, microscopy, etc. Discover how researchers used VCM Technology for their material characterization research projects.

Title	Authors	Company/Institution	Year
Characterization of the temperature and frequency dependency of the complex Poisson’s ratio using a novel combined torsional-axial rheometer	José Alberto Rodríguez Agudo	Anton Paar	2023
Lignin-based benzoxazines: A tunable key-precursor for the design of hydrophobic coatings, fire resistant materials and catalyst-free vitrimers	Antoine Adjaoud	Luxembourg Institute of Science and Technology, University of Luxembourg	2023
The Semicrystalline Morphology of Polybutylene Succinate Supports a General Scheme Based on Intracrystalline Dynamics	Qiang Yu	Martin Luther University	2023
Synthesis and Characterization of Quadrupolar-Hydrogen-Bonded Polymeric Ionic Liquids for Potential Self-Healing Electrolytes	Chenming Li	Martin Luther University	2022
Open-Celled Foams of Polyethersulfone/Poly(N-vinylpyrrolidone) Blends for Ultrafiltration Applications	Aniket Raje	Institute of Membrane Research	2022
Design of Polymeric Zwitterionic Solid Electrolytes with Superionic Lithium Transport	Seamus D. Jones	University of California	2022
Influence of Carbon Dioxide on the Glass Transition of Styrenic and Vinyl Pyridine Polymers: Comparison of Calorimetric, Creep, and Rheological Experiments	Felix Harden	Helmholtz-Zentrum Hereon	2022
How Shape Memory Effects can Contribute to Improved Self-Healing Properties in Polymer Materials	Elizaveta V. Selezneva	A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences	2021
Terahertz Spectroscopy: An Investigation of the Structural Dynamics of Freeze-Dried Poly Lactic-co-glycolic Acid Microspheres	Talia A. Shmool	University of Cambridge, AstraZeneca	2019
Rheology in shear and elongation and dielectric spectroscopy of polystyrene-block-poly(4-vinylpyridine) diblock copolymers	Tarek Kollmetz	Helmholtz-Zentrum Geesthacht	2017

VChamber in Action: Scientific Insights

Explore how the VChamber transforms research with its precise vacuum drying capabilities and adaptability across diverse applications. Discover the latest publications highlighting its impact on innovation and learn how it contributes to groundbreaking advancements in science and technology.

Title	Authors	Company/Institution	Year
Insights into the Capacity Fade of High-Voltage Lithium Cathodes in Solid Polymer Electrolyte Cells	Idan Bar-lev	The Hebrew University of Jerusalem	2025
Enhancing Efficiency, Stability, and Cycle Life of Lithium Metal Electrodeposition in Dry Solid-State Polymer Electrolytes	Idan Bar-lev	The Hebrew University of Jerusalem, Boston University, Ariel University	2024
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024

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