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VCM_HME ASD and implant formulation screening

VCM Publications

MeltPrep accelerates research.

Good sample quality is vital for reliable and reproducible material characterizations. Scientific users and quality managers get the most out of their characterization from flawless samples. VCM is a novel approach to screening polymers using a minimum quantity of active pharmaceutical ingredients. Read our latest publication to find out.

Pharmaceutical Applications

VCM Technology is designed for highly challenging pharmaceutical requirements. Our system's benefits have already attracted the attention of different industries. Read the peer-reviewed publications and explore the different pharmaceutical applications involving VCM Technology.

Title
Authors
Company/Institution
Year
ASD Formation Prior to Material Characterization as Key Parameter for Accurate Measurements and Subsequent Process Simulation for Hot-Melt Extrusion
Kevin Kayser
University of Bonn
2022
A novel anhydrous preparation of PEG hydrogels enables high drug loading with biologics for controlled release applications
Christian E. Ziegler
University of Regensburg
2021
Assessment of the amorphous solid dispersion erosion behavior following a novel small-scale predictive approach
Esther S. Bochmann
AbbVie Deutschland
2021
Novel polyester-based thermoplastic elastomers for 3D-printed long-acting drug delivery applications
Ioannis Koutsamanis
Research Center Pharmaceutical Engineering GmbH, Graz University of Technology
2021
Impact of incorporated drugs on material properties of amorphous solid dispersions
Karsten Flügel
TU Dortmund University, Merck Healthcare KGaA
2021
Novel Cleaning-in-Place Strategies for Pharmaceutical Hot Melt Extrusion
Martin Spoerk
Research Center Pharmaceutical Engineering GmbH
2020
Controlled-Release from High-Loaded Reservoir-Type Systems—A Case Study of Ethylene-Vinyl Acetate and Progesterone
Ioannis Koutsamanis
Research Center Pharmaceutical Engineering GmbH, University of Graz
2020
Developing HME-Based Drug Products Using Emerging Science: a Fast-Track Roadmap from Concept to Clinical Batch
Josip Matić
Research Center Pharmaceutical Engineering GmbH
2020
Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All?
Dunja Novakovic
University of Helsinki
2020
Development of Porous Polyurethane Implants Manufactured via Hot-Melt Extrusion
Ioannis Koutsamanis
Research Center Pharmaceutical Engineering GmbH, University of Graz
2020
Impact of structural relaxation on mechanical properties of amorphous polymers
Karsten Flügel
TU Dortmund University, Merck Healthcare KGaA
2020
Vacuum Compression Molding as a Screening Tool to Investigate Carrier Suitability for Hot-Melt Extrusion Formulations
Gauri Shadambikar
University of Mississippi, Merck KGaA
2020

Material Characterization

Our customers use flawless VCM samples for various measurement methods such as DSC, hardness, notch impact strength, heat capacity, solubility, DMTA, microscopy, etc. Discover how researchers used VCM Technology for their material characterization research projects.

Title
Authors
Company/Institution
Year
Understanding Enhanced Melt Memory in Poly(Octamethylene Carbonate)-Based Random Copolycarbonates with Mixed Isodimorphic/Isomorphic Crystallization
Yilong Liao
Tianjin University, POLYMAT, University of the Basque Country UPV/EHU, Centro de Física de Materiales (CFM-MPC),
2026
Effects of the Environment in Hydrogen-Bonded Polymers
Chenming Li
Martin-Luther-Universität Halle- Wittenberg
2025
Biobased Chemical Recycling: Aminolysis of PET using Renewable Reagents and Monomers to Synthesize New Semi-aromatic Polyamides
Sathiska Kaumadi
Clemson University, Pacific Northwest National Laboratory, University of Delaware
2025
Probing the Influence of Water on the Molecular Mobility of PVP/VA using Terahertz Spectroscopy
Supawan Santitewagun
University of Cambridge
2025
Engineering the Interface of Interfacially-Locked Graphene in Electrically Conductive Poly(ethylene furanoate)/Polyethylene (PEF/PE) Blends
Safa Ahmed
United Arab Emirates University (UAEU), KU Leuven, Eindhoven University of Technology, University of Niagara Falls
2025
Chemical modification of poly(isosorbide carbonate)-based copolymers with boronic acids and the ammonolysis of the modified copolymers
Kazuaki Rikiyama
Chiba University
2025
Effect of Noncrystallizable Comonomers in Polyethylene on Crystallization, Semicrystalline Morphology, Intracrystalline Dynamics, and Linear Mechanical Properties
Shiyan Li
Changchun Institute of Applied Chemistry, Martin-Luther-Universität Halle-Wittenberg
2025
Toughening Brittle Poly(ethylene Furanoate) with Linear Low-Density Polyethylene via Interface Modulation Using Reactive Compatibilizers
Safa Ahmed
United Arab Emirates University, KU Leuven, University of Niagara Falls
2025
Frontal polymerization of thiol–acrylate covalent adaptable networks
Christoph Schmidleitner
Polymer Competence Center Leoben GmbH
2025
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming
Arpan Datta Sarma
Luxembourg Institute of Science and Technology
2024
How entanglements determine the morphology of semicrystalline polymers
Zefan Wang
Martin Luther University
2023
Molecular-Level Control of Thermal and Morphological Transitions in Semi-Aromatic Polyamides by Cu(I)-Catalyzed Azide–Alkyne Click Polymerization
Ozcan Altintas
ExxonMobil Technology and Engineering Company
2023

VChamber in Action: Scientific Insights

Explore how the VChamber transforms research with its precise vacuum drying capabilities and adaptability across diverse applications. Discover the latest publications highlighting its impact on innovation and learn how it contributes to groundbreaking advancements in science and technology.

Title
Authors
Company/Institution
Year
Insights into the Capacity Fade of High-Voltage Lithium Cathodes in Solid Polymer Electrolyte Cells
Idan Bar-lev
The Hebrew University of Jerusalem
2025
Enhancing Efficiency, Stability, and Cycle Life of Lithium Metal Electrodeposition in Dry Solid-State Polymer Electrolytes
Idan Bar-lev
The Hebrew University of Jerusalem, Boston University, Ariel University
2024
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming
Arpan Datta Sarma
Luxembourg Institute of Science and Technology
2024

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