top of page
VCM_HME ASD and implant formulation screening

VCM Publications

MeltPrep accelerates research.

Good sample quality is vital for reliable and reproducible material characterizations. Scientific users and quality managers get the most out of their characterization from flawless samples. VCM is a novel approach to screening polymers using a minimum quantity of active pharmaceutical ingredients. Read our latest publication to find out.

Pharmaceutical Applications

VCM Technology is designed for highly challenging pharmaceutical requirements. Our system's benefits have already attracted the attention of different industries. Read the peer-reviewed publications and explore the different pharmaceutical applications involving VCM Technology.

Title
Authors
Company/Institution
Year
ASD Formation Prior to Material Characterization as Key Parameter for Accurate Measurements and Subsequent Process Simulation for Hot-Melt Extrusion
Kevin Kayser
University of Bonn
2022
A novel anhydrous preparation of PEG hydrogels enables high drug loading with biologics for controlled release applications
Christian E. Ziegler
University of Regensburg
2021
Assessment of the amorphous solid dispersion erosion behavior following a novel small-scale predictive approach
Esther S. Bochmann
AbbVie Deutschland
2021
Novel polyester-based thermoplastic elastomers for 3D-printed long-acting drug delivery applications
Ioannis Koutsamanis
Research Center Pharmaceutical Engineering GmbH, Graz University of Technology
2021
Impact of incorporated drugs on material properties of amorphous solid dispersions
Karsten Flügel
TU Dortmund University, Merck Healthcare KGaA
2021
Novel Cleaning-in-Place Strategies for Pharmaceutical Hot Melt Extrusion
Martin Spoerk
Research Center Pharmaceutical Engineering GmbH
2020
Controlled-Release from High-Loaded Reservoir-Type Systems—A Case Study of Ethylene-Vinyl Acetate and Progesterone
Ioannis Koutsamanis
Research Center Pharmaceutical Engineering GmbH, University of Graz
2020
Developing HME-Based Drug Products Using Emerging Science: a Fast-Track Roadmap from Concept to Clinical Batch
Josip Matić
Research Center Pharmaceutical Engineering GmbH
2020
Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All?
Dunja Novakovic
University of Helsinki
2020
Development of Porous Polyurethane Implants Manufactured via Hot-Melt Extrusion
Ioannis Koutsamanis
Research Center Pharmaceutical Engineering GmbH, University of Graz
2020
Impact of structural relaxation on mechanical properties of amorphous polymers
Karsten Flügel
TU Dortmund University, Merck Healthcare KGaA
2020
Vacuum Compression Molding as a Screening Tool to Investigate Carrier Suitability for Hot-Melt Extrusion Formulations
Gauri Shadambikar
University of Mississippi, Merck KGaA
2020

Material Characterization

Our customers use flawless VCM samples for various measurement methods such as DSC, hardness, notch impact strength, heat capacity, solubility, DMTA, microscopy, etc. Discover how researchers used VCM Technology for their material characterization research projects.

Title
Authors
Company/Institution
Year
Characterization of the temperature and frequency dependency of the complex Poisson’s ratio using a novel combined torsional-axial rheometer
José Alberto Rodríguez Agudo
Anton Paar
2023
Lignin-based benzoxazines: A tunable key-precursor for the design of hydrophobic coatings, fire resistant materials and catalyst-free vitrimers
Antoine Adjaoud
Luxembourg Institute of Science and Technology, University of Luxembourg
2023
The Semicrystalline Morphology of Polybutylene Succinate Supports a General Scheme Based on Intracrystalline Dynamics
Qiang Yu
Martin Luther University
2023
Synthesis and Characterization of Quadrupolar-Hydrogen-Bonded Polymeric Ionic Liquids for Potential Self-Healing Electrolytes
Chenming Li
Martin Luther University
2022
Open-Celled Foams of Polyethersulfone/Poly(N-vinylpyrrolidone) Blends for Ultrafiltration Applications
Aniket Raje
Institute of Membrane Research
2022
Design of Polymeric Zwitterionic Solid Electrolytes with Superionic Lithium Transport
Seamus D. Jones
University of California
2022
Influence of Carbon Dioxide on the Glass Transition of Styrenic and Vinyl Pyridine Polymers: Comparison of Calorimetric, Creep, and Rheological Experiments
Felix Harden
Helmholtz-Zentrum Hereon
2022
How Shape Memory Effects can Contribute to Improved Self-Healing Properties in Polymer Materials
Elizaveta V. Selezneva
A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences
2021
Terahertz Spectroscopy: An Investigation of the Structural Dynamics of Freeze-Dried Poly Lactic-co-glycolic Acid Microspheres
Talia A. Shmool
University of Cambridge, AstraZeneca
2019
Rheology in shear and elongation and dielectric spectroscopy of polystyrene-block-poly(4-vinylpyridine) diblock copolymers
Tarek Kollmetz
Helmholtz-Zentrum Geesthacht
2017

VChamber in Action: Scientific Insights

Explore how the VChamber transforms research with its precise vacuum drying capabilities and adaptability across diverse applications. Discover the latest publications highlighting its impact on innovation and learn how it contributes to groundbreaking advancements in science and technology.

Title
Authors
Company/Institution
Year
Insights into the Capacity Fade of High-Voltage Lithium Cathodes in Solid Polymer Electrolyte Cells
Idan Bar-lev
The Hebrew University of Jerusalem
2025
Enhancing Efficiency, Stability, and Cycle Life of Lithium Metal Electrodeposition in Dry Solid-State Polymer Electrolytes
Idan Bar-lev
The Hebrew University of Jerusalem, Boston University, Ariel University
2024
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming
Arpan Datta Sarma
Luxembourg Institute of Science and Technology
2024

​Ask for support. Our experts are always happy to discuss and explore new applications.

bottom of page