VCM_HME ASD and implant formulation screening

VCM Publications

MeltPrep accelerates research.

Good sample quality is vital for reliable and reproducible material characterizations. Scientific users and quality managers get the most out of their characterization from flawless samples. VCM is a novel approach to screening polymers using a minimum quantity of active pharmaceutical ingredients. Read our latest publication to find out.

Pharmaceutical Applications

VCM Technology is designed for highly challenging pharmaceutical requirements. Our system's benefits have already attracted the attention of different industries. Read the peer-reviewed publications and explore the different pharmaceutical applications involving VCM Technology.

Title	Authors	Company/Institution	Year
Viscosity of ASDs at humid conditions	Friederike Wolbert	INVITE GmbH, TU Dortmund University	2020
Drug eluting implants in pharmaceutical development and clinical practice	Ashley R. Johnson	Merck & Co., Inc.	2020
Novel Screening Tools for Hot Melt Extrusion – Early Prediction of Formulation Performance	T. Kipping	Merck KGaA	2019
Holistic QbD approach for hot-melt extrusion process design space evaluation: Linking materials science, experimentation and process modeling	Rachel C. Evans	AbbVie Deutschland, University of Bonn	2019
Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation	Maximilian Karl	University of Copenhagen, Danish National Research Foundation and Villum Fondens Center	2019
Formulation and processability screening for the rational design of ethylene-vinyl acetate based intra-vaginal rings	Ioannis Koutsamanis	Research Center Pharmaceutical Engineering GmbH, University of Graz	2019
Formulation performance and processability window for manufacturing a dual-polymer amorphous solid dispersion via hot-melt extrusion and strand pelletization	T.R. Hörmann	Graz University of Technology	2018
Establishment of a Molding Procedure to Facilitate Formulation Development for Co-extrudates	Simone Eder	Research Center Pharmaceutical Engineering GmbH	2017
Injection molding as a one-step process for the direct production of pharmaceutical dosage forms from primary powders	Karin Eggenreich	Research Center Pharmaceutical Engineering GmbH	2016
Why hot melts do not stick to cold surfaces	Daniel Treffer	Graz University of Technology	2016
A novel tool to standardize rheology testing of molten polymers for pharmaceutical applications	Daniel Treffer	Research Center Pharmaceutical Engineering GmbH, Graz University of Technology	2015

Material Characterization

Our customers use flawless VCM samples for various measurement methods such as DSC, hardness, notch impact strength, heat capacity, solubility, DMTA, microscopy, etc. Discover how researchers used VCM Technology for their material characterization research projects.

Title	Authors	Company/Institution	Year
Understanding Enhanced Melt Memory in Poly(Octamethylene Carbonate)-Based Random Copolycarbonates with Mixed Isodimorphic/Isomorphic Crystallization	Yilong Liao	Tianjin University, POLYMAT, University of the Basque Country UPV/EHU, Centro de Física de Materiales (CFM-MPC),	2026
Effects of the Environment in Hydrogen-Bonded Polymers	Chenming Li	Martin-Luther-Universität Halle- Wittenberg	2025
Biobased Chemical Recycling: Aminolysis of PET using Renewable Reagents and Monomers to Synthesize New Semi-aromatic Polyamides	Sathiska Kaumadi	Clemson University, Pacific Northwest National Laboratory, University of Delaware	2025
Probing the Influence of Water on the Molecular Mobility of PVP/VA using Terahertz Spectroscopy	Supawan Santitewagun	University of Cambridge	2025
Engineering the Interface of Interfacially-Locked Graphene in Electrically Conductive Poly(ethylene furanoate)/Polyethylene (PEF/PE) Blends	Safa Ahmed	United Arab Emirates University (UAEU), KU Leuven, Eindhoven University of Technology, University of Niagara Falls	2025
Chemical modification of poly(isosorbide carbonate)-based copolymers with boronic acids and the ammonolysis of the modified copolymers	Kazuaki Rikiyama	Chiba University	2025
Effect of Noncrystallizable Comonomers in Polyethylene on Crystallization, Semicrystalline Morphology, Intracrystalline Dynamics, and Linear Mechanical Properties	Shiyan Li	Changchun Institute of Applied Chemistry, Martin-Luther-Universität Halle-Wittenberg	2025
Toughening Brittle Poly(ethylene Furanoate) with Linear Low-Density Polyethylene via Interface Modulation Using Reactive Compatibilizers	Safa Ahmed	United Arab Emirates University, KU Leuven, University of Niagara Falls	2025
Frontal polymerization of thiol–acrylate covalent adaptable networks	Christoph Schmidleitner	Polymer Competence Center Leoben GmbH	2025
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024
How entanglements determine the morphology of semicrystalline polymers	Zefan Wang	Martin Luther University	2023
Molecular-Level Control of Thermal and Morphological Transitions in Semi-Aromatic Polyamides by Cu(I)-Catalyzed Azide–Alkyne Click Polymerization	Ozcan Altintas	ExxonMobil Technology and Engineering Company	2023

VChamber in Action: Scientific Insights

Explore how the VChamber transforms research with its precise vacuum drying capabilities and adaptability across diverse applications. Discover the latest publications highlighting its impact on innovation and learn how it contributes to groundbreaking advancements in science and technology.

Title	Authors	Company/Institution	Year
Insights into the Capacity Fade of High-Voltage Lithium Cathodes in Solid Polymer Electrolyte Cells	Idan Bar-lev	The Hebrew University of Jerusalem	2025
Enhancing Efficiency, Stability, and Cycle Life of Lithium Metal Electrodeposition in Dry Solid-State Polymer Electrolytes	Idan Bar-lev	The Hebrew University of Jerusalem, Boston University, Ariel University	2024
Synthesis of High-Tg Nonisocyanate Polyurethanes via Reactive Extrusion and Their Batch Foaming	Arpan Datta Sarma	Luxembourg Institute of Science and Technology	2024

Ask for support. Our experts are always happy to discuss and explore new applications.

Request a demo

Ask the expert