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VCM_HME ASD and implant formulation screening

VCM Publications

MeltPrep accelerates research.

Good sample quality is vital for reliable and reproducible material characterizations. Scientific users and quality managers get the most out of their characterization from flawless samples. VCM is a novel approach to screening polymers using a minimum quantity of active pharmaceutical ingredients. Read our latest publication to find out.

Pharmaceutical Applications

VCM Technology is designed for highly challenging pharmaceutical requirements. Our system's benefits have already attracted the attention of different industries. Read the peer-reviewed publications and explore the different pharmaceutical applications involving VCM Technology.

Title
Authors
Company/Institution
Year
Viscosity of ASDs at humid conditions
Friederike Wolbert
INVITE GmbH, TU Dortmund University
2020
Drug eluting implants in pharmaceutical development and clinical practice
Ashley R. Johnson
Merck & Co., Inc.
2020
Novel Screening Tools for Hot Melt Extrusion – Early Prediction of Formulation Performance
T. Kipping
Merck KGaA
2019
Holistic QbD approach for hot-melt extrusion process design space evaluation: Linking materials science, experimentation and process modeling
Rachel C. Evans
AbbVie Deutschland, University of Bonn
2019
Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation
Maximilian Karl
University of Copenhagen, Danish National Research Foundation and Villum Fondens Center
2019
Formulation and processability screening for the rational design of ethylene-vinyl acetate based intra-vaginal rings
Ioannis Koutsamanis
Research Center Pharmaceutical Engineering GmbH, University of Graz
2019
Formulation performance and processability window for manufacturing a dual-polymer amorphous solid dispersion via hot-melt extrusion and strand pelletization
T.R. Hörmann
Graz University of Technology
2018
Establishment of a Molding Procedure to Facilitate Formulation Development for Co-extrudates
Simone Eder
Research Center Pharmaceutical Engineering GmbH
2017
Injection molding as a one-step process for the direct production of pharmaceutical dosage forms from primary powders
Karin Eggenreich
Research Center Pharmaceutical Engineering GmbH
2016
Why hot melts do not stick to cold surfaces
Daniel Treffer
Graz University of Technology
2016
A novel tool to standardize rheology testing of molten polymers for pharmaceutical applications
Daniel Treffer
Research Center Pharmaceutical Engineering GmbH, Graz University of Technology
2015

Material Characterization

Our customers use flawless VCM samples for various measurement methods such as DSC, hardness, notch impact strength, heat capacity, solubility, DMTA, microscopy, etc. Discover how researchers used VCM Technology for their material characterization research projects.

Title
Authors
Company/Institution
Year
Characterization of the temperature and frequency dependency of the complex Poisson’s ratio using a novel combined torsional-axial rheometer
José Alberto Rodríguez Agudo
Anton Paar
2023
Lignin-based benzoxazines: A tunable key-precursor for the design of hydrophobic coatings, fire resistant materials and catalyst-free vitrimers
Antoine Adjaoud
Luxembourg Institute of Science and Technology, University of Luxembourg
2023
The Semicrystalline Morphology of Polybutylene Succinate Supports a General Scheme Based on Intracrystalline Dynamics
Qiang Yu
Martin Luther University
2023
Synthesis and Characterization of Quadrupolar-Hydrogen-Bonded Polymeric Ionic Liquids for Potential Self-Healing Electrolytes
Chenming Li
Martin Luther University
2022
Open-Celled Foams of Polyethersulfone/Poly(N-vinylpyrrolidone) Blends for Ultrafiltration Applications
Aniket Raje
Institute of Membrane Research
2022
Design of Polymeric Zwitterionic Solid Electrolytes with Superionic Lithium Transport
Seamus D. Jones
University of California
2022
Influence of Carbon Dioxide on the Glass Transition of Styrenic and Vinyl Pyridine Polymers: Comparison of Calorimetric, Creep, and Rheological Experiments
Felix Harden
Helmholtz-Zentrum Hereon
2022
How Shape Memory Effects can Contribute to Improved Self-Healing Properties in Polymer Materials
Elizaveta V. Selezneva
A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences
2021
Terahertz Spectroscopy: An Investigation of the Structural Dynamics of Freeze-Dried Poly Lactic-co-glycolic Acid Microspheres
Talia A. Shmool
University of Cambridge, AstraZeneca
2019
Rheology in shear and elongation and dielectric spectroscopy of polystyrene-block-poly(4-vinylpyridine) diblock copolymers
Tarek Kollmetz
Helmholtz-Zentrum Geesthacht
2017

VChamber in Action: Scientific Insights

Explore how the VChamber transforms research with its precise vacuum drying capabilities and adaptability across diverse applications. Discover the latest publications highlighting its impact on innovation and learn how it contributes to groundbreaking advancements in science and technology.

​Ask for support. Our experts are always happy to discuss and explore new applications.

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